Fabricating a material that simultaneously exhibits biocompatibility, reusability, and efficient diffusion is a constant challenge in biomaterials research. This poster presents a new class of porous hydrogel material that covalently attaches proteins exclusively on the surface of the pores, and preserves their bioactivity. This novel heterogeneous biocatalyst is made by cross-linking the continuous phase of water-in-water (w/w) emulsions, which are stabilized by different, non-amphiphilic molecular forces. Scanning electron microscopy revealed that hydrogels from w/w emulsions have connected shell-like pores. Higher enzymatic activities and larger diffusion constants were obtained in “connected hydroshell” materials than their non-porous analogs. Confocal fluorescence microscopy showed that proteins are preferably attached on the surface of the pores. With control experiments, our study indicates that pores accomplished by this w/w emulsion can reserve and possibly enhance protein activities, and facilitate efficient diffusion within the hydrogel. Ongoing studies on developing biosensors, control of the formation of biofilm is also presented.