Flavin mononucleotide (FMN), a common redox cofactor, was found to helically wrap around single wall carbon nanotubes (SWNTs), promoting effective aqueous dispersion and individualization. The cooperative H-bonding between adjacent uracil moieties of the isoalloxazine rings result in the formation of a helical ribbon that wraps around SWNTs through concentric pi-pi interactions with the underlying graphene sidewall. This results in a unique redshift pattern depending on nanotube family and modality. In the presence of sodium dodecyl benzene sulfate (SDBS), the FMN helix is disrupted to yield SDBS-micelarized nanotubes without SWNT precipitation, showing self-assembling behavior. This enabled quantification of the relative affinity of the FMN helix on different chirality nanotubes, as a function of SDBS concentration. The significantly stronger affinity of the FMN helix to (8,6)-SWNT was utilized to selectively enrich (85%) this chirality via a simple SDBS replacement and salting-out process from a broad diameter distribution sample, like HiPco.