Through the engineering clinic program, Rowan University and Pfizer have collaborated to explore green engineering alternatives for waste minimization and solvent recovery for the celecoxib process. The current manufacturing process at the Barceloneta, Puerto Rico plant is being evaluated and several green engineering retrofit options proposed. The group has performed a design case study on isopropanol recovery from waste streams with extractive –distillation and pervaporation-distillation techniques. The case study describes equipment and processing issues, and estimates environmental impacts and costs. This project is one of several being conducted by Rowan University as part of the EPA Pollution Prevention initiative in the pharmaceutical industry.