Tuesday, June 24, 2008 - 1:50 PM
New York (Capital Hilton)
36

Greener and Rapid Synthesis of Bio-Active Heterocycles

Vivek Polshettiwar and Rajender, S. Varma. US EPA, Cincinnati, OH

A new kind of chemical revolution “GREEN CHEMISTRY” is brewing, 150 years after the first one transformed modern life with a host of conveniences. It protects the environment, not by cleaning up, but by inventing new chemistry and new chemical processes that do not pollute. The fundamental idea of green chemistry is that the manufacturer of a chemical is responsible for considering what will happen to the human life after the chemical is put in their society [1]. Environmentally benign protocols have been developed for the synthesis of various bio-active heterocycles, which proceed under the influence of microwave irradiation and using eco-friendly conditions[2-7].--------------------------References: (1) Curr. Opin. Drug Discov. Devel. 2007, 10, 723; Acc. Chem. Res. 2008, in press. (2) J. Org. Chem. 2007, 72, 7420. (3) Tetrahedron Lett. 2007, 48, 5649. (4) Tetrahedron Lett. 2007, 48, 7343. (5) Tetrahedron Lett. 2007, 48, 8735. (6) Tetrahedron Lett. 2008, 49, 397. (7) Tetrahedron Lett. 2008, 49, 879.