Amal Sabet Yanni

Chemistry Department, Faculty of Science, Assiut University, Assiut 71526, Egypt

amalyanni@hotmail.com

Tel: 20123971342 (cell), 20882326189 (home), 20882411401 (work)

Representatives of this system belong to a class of biological active compounds and at the same time are excellent starting materials for developing a new type of biological active compounds.

Thermally induced crisscross^1-5 cycloaddition of azines I and II (1 mole) in presence of 2,3-dichloro-1,4-naphthoquinone (2 moles) afforded the adduct III and IV respectively in one-pot reaction. The molecular structure of the products is reported and discussed. The processes for obtaining the title compounds reduce the use and generation of hazardous substances.

I,III a) R = -C₆H₅, b) R = -C₆H₄-p-OCH₃, c) R = -C₆H₄-o-OH,

        d) R = -C₆H₄-p-Cl, e) R = -CH=CH-C₆H₅, f) R = -C₄H₃O

REFERENCES

[1]   Wagner-Jauregg, Ber., 63, 3224 (1930).

[2]   Van Alphen, Rec. Trav. Chem., 61, 892 (1942).

[3]   Amal Sabet Yanni, 16^th International Conference on Physical Organic Chemistry, San Diego, CA, USA, August 4-9 (2002).

[4]   Amal Sabet Yanni, Polymer Networks 2004 Conference, Bethesda, Maryland, USA, August 15-19 (2004).

[5]   Amal Sabet Yanni, 10^th Annual Green Chemistry Conference, Washington DC, USA, June 24-29 (2006).