Conversion of sugar/sugar alcohol to value-added chemicals had been widely studied. Especially for higher sugars, research has been widely exclusively on liquid phase reactions with much emphasis on catalytic hydrogenolysis. The hydrogenolysis reactions are performed at high hydrogen pressure to achieve high conversion and selectivity. In this paper, gas phase catalytic hydrogenolysis is evaluated as a means to overcome liquid phase hydrogenolysis barriers associated with high pressures and catalyst deactivation. Copper-chromite, palladium, and nickel pellet catalysts were screened in gas phase hydrogenation and dehydration of sorbitol and glucose. Complete conversions were attained at reaction pressures of 0.3 to 1bars. The highest selectivities were to acetol.