One way to build complex molecules, such as pharmaceuticals and pesticides, is with a Suzuki “coupling” reaction. This versatile coupling reaction requires precursors with a carbon–boron bond. Making these precursors, however, typically requires harsh conditions and generates significant amounts of hazardous waste. Professors Maleczka and Smith developed a new catalytic method to make these compounds under mild conditions and with minimal waste and hazard. Their discovery allows the rapid, green manufacture of chemical building blocks, including some that had been commercially unavailable or environmentally unattractive.