Preliminary Program subject to change
P450 Metabolism Enzymes
Presentation TypeOral
Summary Statement
Presiders:Donglu Zhang, Bristol-Myers Squibb, Princeton, NJ
Leslie Romanyshyn, Merck & Co., Rahway, NJ
Introductory Remarks
P450 in drug discovery and development - Now and the future
Ronald E. White, Schering-Plough Research Institute, Kenilworth, NJ
The Incorporation of Active and Reactive Metabolite Data into the Drug Discovery Process
Griffith Humphreys, Bristol Myers Squibb Pharmaceutical Research Institute, Princeton, NJ
Break
Human Extrahepatic Cytochrome P450 (CYP) Enzymes: Role in Xenobiotic Metabolism and Toxicity
Jun-Yan Hong, UMDNJ, Piscataway, NJ
Drug-Drug Interactions: P450 Inhibition and Induction
Michael W. Sinz, Bristol_Myers Squibb, Wallingford, CT

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