| Introductory Remarks |
Nonspecific brain binding as an indirect tool to assess CNS penetration Tristan Maurer, Pfizer, Groton, CT |
Human dose projection from pre clinical CNS models: Lundbeck experience Gamini Chandrasena, Lundbeck US Research, Paramus, NJ |
Break |
Application of Physiologically-Based Models in Drug Discovery and Development David Plowchalk, Pfizer, Groton, CT |
Hydrophobic Drug Aggregates: Structure and Biology Eddy Arnold1, Yulia Frenkel2, Arthur D. Clark Jr.1, Kaylan Das2, Yuh-Hwa Wang3, Paul J. Lewi4 and Paul A. J. Janssen2, (1) Rutgers University, Piscataway, NJ, (2)Center for Advanced Biotechnology and Medicine, and Rutgers University, Piscataway, NJ, (3)UMDNJ, Piscataway, NJ, (4)Center for Molecular Design, Belgium |
In Silico Prediction of ADME Properties: Current Status of Predictive Models Terry Stouch, Editor-in-Chief, Hopewell, NJ |