Flavins are found in the active site of APS reductase, an enzyme involved in the dissimilatory sulfate reduction of sulfate to sulfide used by sulfate reducing bacteria in the terminal electron step of their energy production pathway. To mimic this process, our group has synthesized and analyzed several flavin derivatives with amines and amino acids in the R positions, as pictured below. These derivatives will be tested with APS and compared kinetically to the APS reductase found naturally. In this poster, we will present our preliminary results.
Back to Undergraduate Poster Session
Back to The 37th Middle Atlantic Regional Meeting (May 22-25, 2005)