Monday, 23 May 2005: 1:00 PM-4:00 PM

Room 203 (Science & Engineering Resource Center)

Medicinal Chemistry (MEDI)

GPCR / Virtual Screening

This session is intended to cover 4 or 5 30 minute presentations giving an overview of current drug discovery efforts which target G protein-coupled receptors for therapeutic indications.
Organizer:Robert Goodnow
Workshop Leader:Dr. Shawn Erickson
1:00 PM Introductory Remarks Shawn Erickson
1:05 PM Ligand Twisting and Counterion Switching in Rhodopsin Activation
Thomas P. Sakmar
1:35 PM Using Designed Peptide Panels for De-risking GPCR Projects
Waleed Danho
2:05 PM GPCR Ligands from Enzyme Targeted Libraries
Michael Ohlmeyer
2:35 PM Coffee Break
3:00 PM Discovery and Development of the First Centrally Active mGluR5 Positive Allosteric Modulators
Craig Lindsley
3:30 PM A LMW CCR5 Antagonist in Combination with CsA Prolongs Graft Survival in Life Supporting Kidney TX Model in Cynomolgus Monkeys
Gerhard Thoma

Back to The 37th Middle Atlantic Regional Meeting (May 22-25, 2005)