Monday, 23 May 2005: 1:20 PM-5:10 PM

Room 111 (Science & Engineering Resource Center)

Organic Chemistry (ORG)

Bench Top To Pilot Plant II

This one day symposium will be devoted to a discussion on a broad range of topics including process development of small molecules, technologies that address scale-up challenges and case studies dealing with the development of biologics and oligonucleotides.
Organizers:Ambarish Singh
Shankar Swaminathan
1:20 PM Case Study: The Approval of Somavert, a Bio-therapeutic Agent
Amit Banerjee
2:10 PM Process Improvements in Synthesis of Therapeutic Oligonucleotides: From Grams to Kilograms
Yogesh S. Sanghvi
3:00 PM Break
3:15 PM Palladium Coupling Catalysts for Pharmaceutical Applications
Thomas Colacot
3:40 PM Development and Scale-Up of the TACE Inhibitor BMS-561392
Scott A. Savage
4:05 PM The use of SMB as a chiral separation tool from bench to commercial production
Emile Farhan
4:30 PM Preparative supercritical fluid chromatography (SFC) at the kilogram scale
William R. Leonard Jr., Christopher Welch, Jennifer Albaneze-Walker, Mirlinda Biba, Jimmy DaSilva, Derek Henderson
4:55 PM Concluding Remarks

Back to The 37th Middle Atlantic Regional Meeting (May 22-25, 2005)