Tuesday, 6 June 2006: 8:30 AM-12:00 PM
Cocoa 4 (Hershey Lodge and Convention Center)
Analytical Chemistry (ANYL)
Frontiers in Process Analytical Technology
Real-time monitoring of manufacturing processes have long been used by the chemical and food industry in order to ensure the quality of their products. Recently the FDA introduced a new initiative for the pharmaceutical industry described as Process Analytical Technology (PAT) and defined as "a system for designing (product development), analyzing and controlling manufacturing processes, based on timely measurements of critical quality and performance attributes of raw and in-process materials and processes with the goal of ensuring final product quality". The application of this technology includes using at-line, on-line or in-line analysis and monitoring to gain an understanding of a manufacturing process. Advances in PAT methodology and application drive production capabilities, and are critical to scale-up approaches. Similar quality ensuring initiatives have already been extensively used in other industries. This session will feature presentations on PAT approaches in various settings from pharmaceutical and chemical to consumer food producers.
Sponsor: ACS Division of Analytical Chemistry, Bucknell University
Organizer:Charlotte Silverman
Presider:Charlotte Silverman
8:30 AM368Implementation of a new universal HPLC detector in analytical and process development
Darwin Asa
9:00 AM369Development and implementation of PAT in cleaning verification
Anne-Françoise Aubry, Seetha Ananthaiah, Fernando Quiroz, Bhavini Sishta
9:30 AM370PAT in bioprocesses
Humberto Vega
10:00 AM Break
10:20 AM371Applications of quantitative raman monitoring for plant scale API processing
Robert G. Wethman, John Wasylyk, Charles Ray
10:50 AM372Off-line, at-line and on-line blend uniformity analysis on a mass-balanced basis by near infrared spectroscopy
Weiyong Li, Mark Johnson, Rick Bruce
11:20 AM373Optical analyzer for on-line monitoring of oil degradation
Alan M. Schilowitz, Richard Grosser, Gene Sanchez, John Szobota, Walt Vann

Back to The 38th Middle Atlantic Regional Meeting (June 4-7, 2006)