| Monday, 5 June 2006: 1:25 PM-5:30 PM | |||
| Cocoa 6 (Hershey Lodge and Convention Center) | |||
| Organic and Medicinal Chemistry (ORGM) | |||
| Benchtop-to-Pilot Plant | |||
| Designing and implementing a safe and robust process requires a combination of synthetic creativity, development and utilization of new technologies, and effective engineering. Speakers in this session will address recent challenges in pharmaceutical process chemistry and their strategies for a successful, scalable process. | |||
| Sponsor: | Pfizer | ||
| Organizer: | Jennifer Rutherford | ||
| Presider: | Jennifer Rutherford | ||
| 1:25 PM | Introductory Remarks | ||
| 1:30 PM | 202 | Tailored solutions for the formation of amide bonds in large scale Silvina García Rubio | |
| 2:05 PM | 203 | Application of flow microreactor technology in process research Xini Zhang | |
| 2:40 PM | 204 | Development of a Practical Synthesis of a GABAa á 2,3-Selective Allosteric Modulator R. Scott Hoerrner, Mark S. Jensen, Wenjie Li, Dorian P. Nelson, Gary J. Javadi, Peter G. Dormer, Dongwei Cai, Robert D. Larsen | |
| 3:15 PM | Break | ||
| 3:25 PM | 205 | AEW541: A Challenge to Process Chemists Joel S. Slade, Joginder Bajwa, Kapa Prasad, Hui Liu, John Calienni, James Vivelo, David Parker, Guang-Pei Chen, Edwin Villhauer | |
| 4:00 PM | 206 | Integration of Lithiation and Coupling Reactions into a Continuous Process as an Alternative to a Cryogenic Batch Synthesis Chenchi Wang, Prashant Deshpande, Wendy Yang, Thomas LaPorte | |
| 4:35 PM | 207 | Process development and large-scale synthesis of a PDE-IV inhibitor Brenda Pipik, David A. Conlon, Antoinette Drahus-Paone, Guo-Jie Ho, Roy Helmy, Yao-Jun Shi, James M. McNamara, J. Michael Williams | |
| 5:10 PM | 208 | Air-stable Palladium-Phosphine based catalysts for challenging Carbonylation and Coupling reactions Thomas Colacot | |
Back to The 38th Middle Atlantic Regional Meeting (June 4-7, 2006)