Tuesday, 6 June 2006: 8:10 AM-12:00 PM
Magnolia C-D (Hershey Lodge and Convention Center)
Organic and Medicinal Chemistry (ORGM)
MARM Honors: The Alfred Burger Award, Part I
This symposium honors the ACS Division of Medicinal Chemistry Burger Award and consists of three invited speakers who have won this national award, three additional invited speakers, and a select number of contributed papers.
Sponsor: ACS Division of Medicinal Chemistry and Merck and Co
Organizer:Stephen C. Waller
Presider:Alan Cooper
8:10 AMIntroductory Remarks
8:15 AMSynthesis and Evaluation of Conformationally-Constrained Analogs of the Analgesia Enhancing Agent MD-354
Eliseu O. De Oliveira, Shawquia E. Young, Richard A. Glennon, Malgorzata Dukat
8:40 AMThe synthesis and preliminary evaluation of sydnone analogues of Celebrex and Vioxx
Charles J. Thoman, John R. Porter, Christopher S. Dunkley
9:05 AMHigh Affinity InhA Inhibitors that show Activity against Drug-Resistant Strains of Mycobacterium tuberculosis
Todd J. Sullivan, James J. Truglio, Polina Novichenok, Caroline Kisker, Francis Johnson, Richard A. Slayden, Peter J. Tonge
9:30 AMBreak
9:45 AMDiscovery of JANUVIA™ (sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
Ann E. Weber
10:30 AMPsymberin (irciniastatin A) via spirodiepoxide
Lawrence J. Williams
11:15 AMNatural product synthesis via some classic reactions
Erik Sorensen

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