Jacob C. Laas, Robert R. Pavlis, Nancy L. Brooker, and Yury V. Kuzmichev. Pittsburg State University, Pittsburg, KS
Soybean seedlings are subject to attack by several types of fungi. Sesamol (3,4-(methylenedioxy)phenol) is a fairly effective agent for seed treatment to prevent such attacks. In this work, a variety of coumarin derivatives were produced for screening as potential anti-fungal agents because of their similarity in shape to sesamol.
Most of the compounds that were produced were derived from 4-hydroxy- and 7-hydroxy-coumarin. The synthesis and activity of each compound will be presented.
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