Thursday, November 8, 2007: 1:00 PM-5:00 PM
Salon II (Intercontinental at the Plaza)
Symposium on Chemical Methodologies and Library Development
Chemical libraries are now established as important tools for the discovery of novel biological probes and drugs, catalysts, and materials. In early days, library synthesis utilized a relatively small set of chemical reactions that were robust, reliable, and, in many cases, amenable to solid phase synthesis. Examples of these reactions would have included amide bond formation, thermal cycloaddition chemistry, and multicomponent reactions such as the Ugi process. As the need for more sophisticated libraries grows, so grows the need to expand the toolbox of reactions that can be used in their construction. Speakers in the present symposium will present a variety approaches to extend chemistry that facilitates library synthesis.
Presider:Jeffrey Aubé
Organizer:Jeffrey Aubé
1:00 PM Welcoming Remarks
1:05 PM262ROM Polymerization Strategies toward Diverse Sultam Libraries
Paul R. Hanson
1:45 PM263A New Multicomponent Synthesis of Polysubstituted γ-Lactams
Jared T. Shaw
2:25 PM264Recent Advances in High-Throughput Organic Synthesis for Drug Discovery
Daryl R. Sauer
3:05 PM Break
3:15 PM265Heterocycles: Here to There and Back
Mark J. Kurth
3:55 PM266The Bicyclobutane Gateway to Heterocycles
Peter Wipf

Back to The Midwest Regional Meeting (November 7 – 10, 2007)