Thursday, 14 July 2005 - 1:30 PM
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This presentation is part of: Analytical Chemistry

Determination of a Contraceptive Constituent, Ethinylestradiol, and Its Photodegradation in Natural Surface Water

Yuegang Zuo1, Kai Zhang1, and Yiwei Deng2. (1) University of Massachusetts Dartmouth, North Dartmouth, MA, (2) University of Michigan-Dearborn, Dearborn, MI

The presence of estrogenic compounds in aquatic environment has become of increasing concern during the past decade due to their endocrine disruption potential. Among these estrogenic chemicals, a group of synthetic steroids is of particular concern. This concern raises in part from the increasing use of birth-control pills, formulated with exogeneous estrogenic and progestational chemicals that show high physiological activity at very low concentrations and have been associated to certain alarming effects on reproduction and developmental processes such as feminization, decreased fertility or hermaphroditism. In this study, 17a-ethinylestradiol (EE2), a major constituent of common contraceptive pills, and two other estrogenic hormones, estrone (E1) and 17b-estradiol (E2), have been determined in Acushnet River Estuary seawater using a GC-MS technique. Among three estrogenic compounds detected, EE2 has the highest concentration, up to 4.7 ng/L, at which EE2 may affect lobster and other fish abundance in the coastal seawater due to its high biological activity on fish feminization. Although EE2 is persistent to microbial degradation, it can undergo a rapid photodegradation in the estuarine seawater under natural sunlight irradiation, with a half-life of less than 1.5 days in the spring sunny days.



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