Friday, 15 July 2005
76

This presentation is part of: Analytical Chemistry Poster Session

Advances in LC/ICP-MS Speciation

Wilhad M. Reuter, PerkinElmer LAS, Shelton, CT

High-performance liquid chromatography (HPLC) coupled to an ICP-MS has become an invaluable analytical tool for the determinations of trace levels of individual arsenic and chromium compounds (speciation). Speciation of arsenic, chromium and other elements is now being used to improve our knowledge of these element's biochemical interactions and to evaluate toxicity risks. The impetus for this is that it is increasingly recognized that the toxicity/bioavailability of various elements is highly dependent on the form or species it is found in. For example, whereas arsenobetaine (AsB) is relatively non-toxic, arsenic (III) and arsenic (V) are both quite toxic. With the above in mind, this poster highlights currently developed speciation methods and corresponding practical considerations.

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