Vibrational optical activity (VOA) is comprised of two principal techniques, infrared vibrational circular dichroism (VCD) and vibrational Raman optical activity (ROA). In this presentation, we report on recent advances in VOA spanning the mid-infrared to the near-infrared spectral regions. In the mid-IR we will report several new intriguing applications of enhanced VCD spectra. These include spray-dried samples of amino acids and molecules of pharmaceutical interest, the dynamics of protein fibrillation, and magnetic VCD in transition metal complexes with low-lying excited states. We have extended FT-VCD measurements from the mid-IR to the near-IR as far as 14,000 cm-1 demonstrating the feasibility of FT-CD measurements in the visible region of the spectrum. Finally, we report the extension of ROA from excitation at 532 nm in the visible region to excitation at 780 nm in the near-IR region where applications involving the measurement of surface-enhanced ROA (SEROA) of chiral molecules on near-IR tuned nanoshells as SERS substrates is an immediate objective.