Nanochemistry is the study of chemistry with nanoscale structures. Studies of the syntheses, properties, and chemical applications of molecular structures such as nanoparticles, nanocrystals, nanotubes, and molecular assemblies fall into nanochemistry field. Materials at nanoscale can produce substances with fundamental different properties and behavior. This field is considered as one of the 10 emerging technology by Technology Review(TR, March/April, 2006). We have designed nanochemistry for undergraduate students at Tsinghua University while on my sabbatical leave there. The first one was offered for the spring semester of 2005 as an elective. The second one was built in the four year chemistry curriculum. For the first course, a basic introduction to nanoscience including nano-therapeutic devices, nanomedicine, nanocomposites, nanoceramics, carbon nanotubes, electrochemistry, surface chemistry in nanoscale, and a review of instrumentations as applied to the study of nanomaterials. This category includes scanning probe microscopy (SPM), especially the atomic force microscopy (AFM). The second part of the nanochemistry in undergraduate curriculum was built in chemistry course from general, inorganic, organic, and physical chemistry throughout the whole four years of study.