Dannon J. Stigers1, Gary R. Weisman1, Edward H. Wong1, Jonathan M. White2, and Carolyn J. Anderson3. (1) University of New Hampshire, Durham, NH, (2) University of Melbourne, Parkville, Australia, (3) Washington University School of Medicine, St. Louis, MO
An unusually high yielding monoalkylation of cross-bridged cyclam (1) has been developed in order to produce monoamide 2. Synthetic routes for many mixed pendant-armed derivatives via 2 will be presented. The Cu(II) complexes of some of these ligands have been synthesized and characterized.

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