Thursday, 5 October 2006
South Ballroom (Binghamton Regency Hotel and Conference Center)
141

Nucleophilic reductions triggered by telluride ion: synthesis of tetramic and tetronic acid derivatives

Donald C. Dittmer, Dmitry V. Avilov, Matthew T. Purzycki, Zachary J. Martens, Elliot B. Hohn, Qun Li, and Matthew W. Bacler. Syracuse University, Syracuse, NY

Elemental tellurium is a useful and recoverable reagent in nucleophilic reductions by telluride ion which involves attack by the strongly nucleophilic  anion at an electrophilic site in certain organic compounds which triggers a formal reduction of the compound with concomitant formation of elemental tellurium: This nucleophilic reduction process is applied to the synthesis of tetramic and tetronic acids and their derivatives starting with amino acids or hydroxycarboxylic acids.

 


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