Turbulent flow reactor data are reported on the destruction of diethyl sulfide, a simulant for mustard chemical warfare agents. Liquid diethyl sulfide was metered with a syringe pump into a nitrogen flow; this mixture was then injected into a larger, heated nitrogen flow, producing initial loadings between 400 and 800 ppm. Experiments were performed in a quartz-lined flow reactor of ID 4.2 cm and length 80 cm. Samples were extracted from ports along the flow reactor and analyzed by FTIR. The following products were observed: ethanethiol, carbon disulfide, thiophene, and light hydrocarbons. Experimental data are compared to plug flow calculations with a detailed chemical kinetic model. Important chemical reaction paths are described.