The village of Endicott, located in the greater Binghamton NY area, has a population of about 13,000 and is known as the birthplace of IBM. At its height, Endicott's IBM facility covered 150 acres and employed over 12,000 people. In 1979, IBM reported a spill of 4,100 gallons of 1,1,1-trichloroethane (TCA). This event marked the beginning of 25 years of revelations of increasing amounts of toxins, primarily trichloroethene (TCE), in the environment and of deleterious effects on resident's health. To date, more than 350 metric tons of volatile organic compounds have been extracted from the site. In terms of number of homes and people affected, the Endicott spill is now the largest toxic spill in New York State. This talk provides a timeline of events leading up to and subsequent to the reported spill, and an overview of the scientific, legal, political, and sociological issues surrounding the spill.