Advances in Raman instrumentation and the ease of use of modern micro-Raman instruments have allowed Raman microscopy to become a routine method of chemical analysis in an optical microscope. In an optical microscope single point analysis Raman spectroscopy is simple and fast in sample regions that show high optical contrast. The use of programmable motorized stages on the optical microscope allowing Raman microscopy to survey large areas has become popular and the methods for obtaining Raman images for chemical contrast. Unfortunately, Raman imaging for chemical analysis becomes very time intensive if optical contrast methods cannot identify different regions of interest. As Raman imaging remains a time intensive spectroscopic method it is generally not well suited to surveying large areas where there are potentially unknown constituents. Fortunately, Raman spectroscopy can be incorporated into non-optical microscopes, for example scanning electron microscopes and atomic force microscopes. The scanning electron microscope and atomic force microscope support a number of “fast” chemical and topographical contrast methods that can greatly simplify area composition distribution analysis. Examples and advantages of Raman imaging using optical and non-optical microscopes will be discussed.