Microflow(i) and Microwave(ii) in its amendment to continuous synthesis are newly evolving “physico-chemical reagents”. Beyond accelerating the chemical reaction, microflow brought sequential organic synthesis to enhance chemistry research output. This paper shall discuss recent applications of microflow and continuous microwave with improved performance as they pertain to typical synthesis schemes in library synthesis. It shall briefly give a rationale for these findings and discuss applications and state of technology in accelerating information gathering and library synthesis with continuous synthesis technology.

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