Recently there has been a growing interest in C-H insertion and direct arylation reactions as an alternative to cross-coupling methods. C-H insertion reactions are advantageous as they eliminate the use of stoichiometric amounts of potentially environmentally harmful organometallic reagents, thereby making these insertion reactions a greener alternative to conventional cross-coupling methods. In addition, they are also more efficient in that the steps required to prepare these organometallic reagents are avoided. The pyridine ring is an important moiety ubiquitous in Nature and in other pharmaceutically active compounds. Furthermore it can be a precursor to the piperidine ring, which has also been demonstrated to be an active constituent in a wide variety of biological functions. However, cross-coupling reactions involving the 2-position of the pyridine ring have been known to be difficult due to the poor electron density at that site. This work focuses on the use of direct arylation reactions on sp2 and sp3 centres of pyridine and pyridine derivatives. The use of C-H insertion methodology provides a tool in the synthesis of pyridine derivatives otherwise inaccessible by cross-coupling reaction. Furthermore, it provides an example of direct arylation on sp3 carbon atoms, which has little precedent in the literature. An N-iminobenzoyl group is believed to act as a directing group for the palladium-catalyzed insertion. These arylation reactions make use of a variety of aryl halides and give the arylated products in good to excellent yields