Monday, June 30, 2008: 9:00 AM-12:05 PM
Kingsland Room (Sheraton Burlington Hotel and Conference Center)
Peptides as Tools to Study Protein Function I
This symposium focuses on the use of peptides to study protein function. This includes:

The use of peptides as enzyme inhibitors
Peptides as receptor agonists/antagonists
Peptides as therapeutics agents
Peptides as protein structure/function probes
The use of peptides to probe enzyme reaction mechanisms
Peptide chemistry and synthetic methodologies as they broadly relate to protein function.
Organizer:Robert J. Hondal
9:00 AMFolding of a Beta-Clam Protein: From the Test Tube to the Cell
Lila M. Gierasch, Kenneth S Rotondi, Anne Marie Marcelino, Beena Krishnan, Jiang Hong, Ivan Budyak, Harekrushnoo Sahoo, Qinghua Wang, Zoya Ignatova
9:45 AMNative Chemical Ligation as An Important Tool in Protein Engineering
Stevenson Flemer Jr., Robert J. Hondal
10:15 AMBreak
10:35 AMUnderstanding the Mechanism of SH3 Domain Binding to Peptide Using NMR Spectroscopy
Jean-Philippe Demers, Anthony Mittermaier
11:05 AMConformational Analysis of N-Me Vicinal Disulfide Rings and Vicinal Diselenide Ring Reveal B-Turn Mimics
Erik Ruggles, Robert Hondal
11:35 AMAdvances In 1) the Development of New Deprotection Chemistry for Cysteine and Selenocysteine Side Chain Protecting Groups and 2) the Synthesis of a New Selenocysteine Derivative That Have Applications In Peptide Synthesis
Alayne Schroll, Robert Hondal

Back to The Northeast Regional Meeting (NERM) (June 29 - July 2, 2008)