Wednesday, 18 October 2006: 8:30 AM-12:00 PM
Bonsai (Doubletree Hotel at Reid Park)
Molecular Origami: Conformation in Chemistry and Biochemistry
Organizer:John J. Osterhout
Presider:John J. Osterhout
8:30 AMIntroductory Remarks
8:35 AMMeasuring the Energetic Balance Between Helix Formation and Hydrophobic Interactions
Wujing Xian, Peter J. Connolly, Marcela Oslin, Andrew C. Hausrath, John J. Osterhout
8:55 AMDirected Evolution of a beta-sheet Scaffold for Targeting Protein Surfaces
Srivats Rajagopal, Scott C Meyer, Aaron J Goldman, Thaddeus J Smith, Min Zhou, Clifford I Stains, Indraneel Ghosh
9:15 AMSyzygy: A statistical thermodynamic model describing beta-sheet formation
Andrew C. Hausrath
9:35 AMAlzheimer's disease at the cell border: characterizing the interaction of the Alzheimer's amyloid beta peptide with lipid membranes
Jennifer R. Bethke, Savitha Devanathan, Gordon Tollin, John J. Osterhout
9:55 AMBreak
10:20 AMSweet entanglement: role of multivalent binding to oligomannosides in the antiviral activity of cyanovirin
Giovanna Ghirlanda
10:40 AMDesign, structure-activity relationships and biological evaluation of novel bifunctional C-terminal modified peptides for opioid receptor agonists and Neurokinin-1 receptor antagonists
Takashi Yamamoto, Padma Nair, Shou-wu Ma, Sharif Moye, Peg Davis, Tally Largent, Richard Egleton, Todd W. Vanderah, Josephine Lai, Frank Porreca, Henry I. Yamamura, Victor J. Hruby
11:00 AMStructure of Substrate Protein in Small Heat Shock Protein (sHSP)/Substrate Complexes Characterized by Solution Phase Hydrogen/Deuterium Exchange and Mass Spectrometry
Guilong Cheng, Elizabeth Vilering, Vicki H. Wysocki
11:20 AMDesign and Synthesis of Homodimers of MSH Ligands with Flexible, Semi-rigid and Rigid Linkers
Rajesh Sankaranarayanan, Jatinder Josan, Yasunari Monguchi, Heather Handl, Liping Xu, Josef Vagner, Eugene Mash, Robert Gillies, Victor Hruby
11:40 AMQuaternary Structural Analysis of Small Heat Shock Proteins by Mass Spectrometry: Chemical Biology in the Gas-Phase
Christopher M. Jones, Richard L. Beardsley, Eman Basha, Heather A. O'Neill, Guilong Cheng, Nomalie Jaya, Asiri S. Galhena, Shai Dagan, Elizabeth Vierling, Vicki H. Wysocki

Back to The 19th Rocky Mountain Regional Meeting (October 14-18 2006)