| Wednesday, 1 November 2006: 1:00 PM-5:30 PM | |||
| Lamar C (Augusta Marriott Hotel and Suites) | |||
| Biological Chemistry (6) | |||
| Chemistry of aging (MEDI, BIOL) | |||
| Aging is characterized by gradual changes in the structure, function and turnover of proteins. The rate of these changes is regulated, in part, by hormonal mechanisms. This session will address proteomic analysis of oxidative modifications of brain proteins in Alzheimer's disease, mechanisms of recognition and regulation of turnover of modified proteins by the ubiquitin-proteasome pathway, the broad nature of chemical modifications of protein during aging, and the role of insulin-like growth factors in regulation of aging in a mouse model of accelerated aging. | |||
| Sponsor: | ACS Division of Medicinal Chemistry | ||
| Organizer: | John Baynes | ||
| Presiders: | John W. Baynes D. Allan Butterfield | ||
| 1:00 PM | 105 | Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this dementing disorder D. Allan Butterfield | |
| 2:00 PM | 106 | Protein quality control; structure and function of ubiquitin binding proteins Keith D. Wilkinson | |
| 3:00 PM | 107 | Nonenzymatic modification of tissue proteins during aging Norma Frizzell, Ryoji Nagai, Sandra P. Melo, Suzanne R. Thorpe, John W. Baynes | |
| 4:00 PM | 108 | Novel Interaction between Insulin-like Growth factor-1 (IGF-1) and Sirtuin Type-1 (SirT1) in the cell nucleus Bernhard F. Maier, Michal Sabat, Katarzyna D. Koclega, Maksymilian Chruszcz, Cyrille Gineste, Christopher Thorston, Wladek Minor, Heidi Scrable | |
Back to The 58th Southeast Regional Meeting (November 1-4, 2006)