Thursday, 2 November 2006: 8:25 AM-12:00 PM
Hamilton A (Augusta Marriott Hotel and Suites)
Biological Chemistry (6)
Frontiers in nucleic acids chemistry III (BIOL)
Sponsor: ACS Division of Biological Chemistry
Organizer:Nicholas V. Hud
Presider:Roger Wartell
8:25 AMIntroductory Remarks
8:30 AMTowards the characterization of DNA binding inhibition of a small peptide by Distamycin A
Karen L. Buchmueller, Lawrence Ngo, Meredith Parkinson, Christopher Vellano
9:05 AMInduced fit and bound water provide strong interactions in the DNA minor groove complex of a highly twisted benzimidazole diamidine
W. David Wilson, Farial Tanious, Kristie Goodwin, Millie Georgiadis, William Laine, Paul Peixoto, Christian Bailly, Richard R. Tidwell
9:40 AMNMR spectroscopy of stereoisomeric N3-(2-hydroxy-3-buten-2-yl)-2'-deoxyuridine DNA adducts arising from butadiene monoepoxide
Sarah K. Musser, Ivan D. Kozekov, Richard P. Hodge, Carmelo J. Rizzo, R. Stephen Lloyd, Michael P. Stone
10:00 AMBreak
10:15 AMThoughts on the binding of small molecules to intramolecular folded DNAs including hairpin, i-motif and G-quadruplex constructs: the role of water revisited
Edwin A. Lewis, Matthew W. Freyer, Robert Buscaglia
10:50 AMRecognition of A and B-form nucleic acids
Dev P. Arya, Hongjuan Xi, Nick Shaw
11:25 AMUse of a novel Förster resonance energy transfer method to measure site-binding of metal ions in the U2-U6 snRNA complex
Nancy Greenbaum, Faqing Yuan, Laura Griffin, Laura Jane Phelps, Volker Buschmann

Back to The 58th Southeast Regional Meeting (November 1-4, 2006)