Thursday, 3 November 2005: 1:30 PM-5:00 PM

Lansdowne (Peabody Hotel)

Symposium (SYMG)

Frontiers in Nucleic Acid Chemistry II

Session II. The symposium “Frontiers in Nucleic Acid Chemistry” marks the 20th anniversary of the highly successful Southeastern DNA Group meetings first organized in 1985. Traditionally the DNA symposium has been concurrently held in conjunction with the Southeast Regional Meeting of the American Chemical Society (SERMACS). The meeting provides an excellent mix of cutting-edge science focused in nucleic acid chemistry, structural biology and biophysical chemistry. This year, Frontiers in Nucleic Acid Chemistry will specifically focus on the structure and stability of a variety of nucleic acid structural motifs and nucleic acid-ligand complexes from many of the top nucleic acid scientists throughout the nation. For additional information and/or questions regarding this symposium, please contact the organizers, David Graves of the University of Alabama-Birmingham (dgraves@uab.edu) or Jonathan B. Chaires (j.chaires@louisville.edu).
Organizers:David Graves
Jonathan B. Chaires
David E. Graves
Presider:Michael P. Stone
1:30 PM342Drug Binding to G-Quadruplex and I-Motif DNA Structures
Edwin A. Lewis, Robert Buscaglia, Matthew W. Freyer
2:00 PM343DNA Damage: Insights into Substrate Recognition by Endonuclease IV
Markus W. Germann
2:30 PM344DNA Topology Alters the Response of Human Topoisomerases to Anticancer Drugs
A. Kathleen McClendon, Neil Osheroff
3:00 PM Intermission
3:10 PM345Single Nucleotide RNA Choreography
Loren Dean Williams, Chiaolong Hsiao, Srividya Mohan
3:40 PM346Biological and Biophysical Properties of Quadruplex Forming Oligonucleotides
Paula Bates, John Trent, Donald Miller, Jonathan B. Chaires, Alison Roger
4:10 PM347Out of Shape Compounds: Unusual Interactions in the DNA Minor Groove
W. David Wilson, Yi Miao, Binh Nguyen, Farial Tanious, Mohamed A. Ismail, Adalgisa Batista-Parra, David W. Boykin, Michael P. H. Lee, Stephen Neidle

Back to The 57th Southeast/61st Southwest Regional Meeting (November 1-4, 2005)