This project seeks to functionalize carbon nanotubes (CNTs)
through the use of designed peptides. We have developed a series of amphiphilic
alpha helical peptides which are able to bind to CNTs, effectively dispersing
them in solution. In this project, we will compare the binding affinities of
two of these peptides; nano-1 (containing Val in a positions and Phe at d
positions of a heptad repeat) versus (HaFd)4
(a derivative of Nano-1 with His located in the a position and Phe in
the d position). Preliminary results of CD spectroscopy of (HaFd)4
alone show molar ellipticity increases with increased peptide
concentration. An increase in molar ellipticity was also observed to be linked
to decreases of pH in solution, although further experimentation must be done
in order to verify these results. The ability of the peptides to disperse CNTs
in solution, as well as the CD of the resulting peptide/CNT dispersions, will
also be determined and discussed.