78 Structure Analysis and Transmetallation of Supramolecular Assemblies Incorporating Phosphorus, Arsenic, Antimony, and Bismuth

Wednesday, November 4, 2009: 3:30 PM
Angus (Camino Real Hotel)
Virginia M. Cangelosi , Department of Chemistry, University of Oregon, Eugene, OR
Lev N. Zakharov , Department of Chemistry, University of Oregon, Eugene, OR
Darren W. Johnson , Department of Chemistry, University of Oregon, Eugene, OR
Arsenic, infamous for its toxicity, is a naturally-occurring contaminant of drinking water across the world.  Unfortunately, there are no chelators that are specific to arsenic which highlights the need for more fundamental research in the area.  Taking a supramolecular approach, we have prepared a series of Group 15 element-containing cryptands E2L3 (E = As, Sb, Bi; H2L = 1,4-bis(mercaptomethyl)naphthalene).  The crystal structures of these compounds allow direct comparison of the bond geometry preferences of these Group 15 elements.  We have also found that these bridgehead elements can be replaced by transmetallation.  This exchange allows access to a P2L3 cryptand which could not be prepared by previous methods.