280 Chiral Crabtree Catalyst Analogs for Syntheses of Valuable Chirons

Thursday, November 5, 2009: 9:25 AM
Longhorn (Camino Real Hotel)
Kevin Burgess, Professor , Department of Chemistry, TAMU, College Station, TX
Hydrogenation of “largely unfunctionalized” alkenes has been an active area of research for about a decade. Many catalysts have been prepared but we noticed that comparatively few substrates have been studied. That motivated us to investigate asymmetric hydrogenations of dienes and polyenes. It emerged that such reactions could provide a concise entry points into chirons for that can be used to prepare many natural products. This talk will discuss our chiral carbene catalyst system for hydrogenation of largely unfunctionalized alkenes, applied to prepare widely used chirons for organic syntheses.
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