Wednesday, November 4, 2009: 4:10 PM
Charolais (Camino Real Hotel)
Although herbal medicine is widely employed in inhibition of urinary calculi as an alternative and complementary curative method, the lack of detailed scientific studies that could provide insights into this complex process weakens its validity. The present work targets multi-technique spectroscopic investigations by Raman, infrared absorption, X-ray photoelectron spectroscopy (XPS), and photoluminescence on the effects of the herb Rotula Aquatica Lour (RAL) on the growth of synthetically prepared manganese-based calculi. In addition to the standard magnesium phosphate – based sample, two other samples were prepared with incorporation of 1% and 2% wt.% RAL herbal extract. Both, Raman and infrared data show a newberyite structure for the crystals without and with inhibitor. The XPS measurements reveal an unexpected presence of Zn in the sample with RAL inhibitor, which, as suggested in the literature, may initiate rapid stone formation, and consequently, contribute to the inhibition process. A significant increase in magnesium with addition of herbal extract is observed in the XPS data. Also, evidence for Mg-O binding between the inhibitor and the phosphate units of urinary calculus is found in XPS and Raman results. Similarity between our photoluminescence measurements and those of in vivo chlorophyll corroborates to provide additional evidence of Mg-related inhibition.