Monday, 23 May 2005
317

This presentation is part of: Bench Top to Pilot Plant Posters

Implementation of HPLC Automation for the Analysis and Purification of Chiral Molecules

Craig K. Esser, Regina M Black, and Derek Von Langen. Merck Research Laboratories, Rahway, NJ

An HPLC automation strategy was developed and implemented in a big pharma research department of 200+ medicinal chemists for the analysis and purification of chiral molecules. Discussions of why a decentralized, Open-Access HPLC strategy was chosen over a centralized, Expert-Only strategy will be presented, and why certain HPLC hardware and software was selected to implement this strategy. Finally, we will offer the reasons why we were successful with implementing our HPLC automation.

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