Wednesday, 25 May 2005: 9:00 AM-12:00 PM

Room 209 (Science & Engineering Resource Center)

Analytical Chemistry Frontiers (ANAL)

Functional Proteomics, Cell Signaling and Disease Biomarkers

Recent technical advances in mass spectrometry have made it possible to obtain much useful information about small amounts of proteins in biomedical experiments. This session will provide examples of the use of mass spectrometry for the study of key intracellular signaling processes, including events such as protein phosphorylation downstream of receptor tyrosine kinases. The session will also provide examples of the use of mass spectrometry for the discovery of biomarkers for the diagnosis and characterization of disease states.
Workshop Leader:Thomas A. Neubert
9:00 AM Novel Multiplexed CSF Biomarkers for Antemortem Alzheimer's Diagnosis
Kelvin H. Lee, Erin Finehout, Zsofia Franck, Leila Choe, Norman Relkin
9:30 AM Serum peptide signatures of solid tumor cancers
Paul Tempst, Josep Villanueva
10:00 AM A Mass Spectrometry-Based Quantitative View of Protein Phosphorylation
Roland S. Annan, Francesca Zappacosta, Dean McNulty, Micheal Huddleston, Therese Sterner
10:30 AM Break
10:45 AM The identification of possible blood proteins as biomarkers for atherosclerotic plaque
Stanley A. Hefta
11:15 AM Functional Proteomics of Ephrin Signaling
Thomas A. Neubert, Daniel S. Spellman, Guoan Zhang

Back to The 37th Middle Atlantic Regional Meeting (May 22-25, 2005)